Thalidomide-O-amido-PEG3-C2-NH2
CAS No. : 1957236-20-2
(Synonyms: Cereblon Ligand-Linker Conjugates 3 ; E3 Ligase Ligand-Linker Conjugates 14)
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| Cat. No. : | HY-107440 |
| M.Wt: | 506.51 |
| Formula: | C23H30N4O9 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology. In Vitro: Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is composed of Degron (E3 ubiquitin ligase) and a linker, and they are used in PROTAC technology. Thalidomide-O-amido-PEG3-C2-NH2 binds to the targeting ligand to induce the target protein (including BRD4, BRD2, and BRD3) degradation[1].
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