Blarcamesine
CAS No. : 195615-83-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $70 | In-stock |
| 25mg | $130 | In-stock |
| 50mg | $220 | In-stock |
| 100mg | $370 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-105296 |
| M.Wt: | 281.39 |
| Formula: | C19H23NO |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Blarcamesine is an orally bioavailable Sigma-1 receptor agonist and muscarinic receptor modulator, with anticonvulsant, anti-amnesic, neuroprotective and antidepressant properties. Blarcamesine ameliorates neurologic impairments in a mouse model of Rett syndrome[1].
IC50 & Target:Sigma-1 receptor, muscarinic receptor[1]
In Vivo: Blarcamesine (10 mg/kg, 30 mg/kg; p.o.; daily; for 6.5 weeks) ameliorates motor deficits in Mecp2 HET mice with chronic administration[1].
Blarcamesine ameliorates acoustic startle deficit in Mecp2 HET mice[1].
Blarcamesine reverses deficits in visual acuity in older Mecp2 HET mice using the optokinetic response[1].
Blarcamesine produces minimal effects on body weight gain in Mecp2 HET mice[1].
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