SB 258719
CAS No. : 195199-95-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $105 | In-stock |
| 10mg | $168 | In-stock |
| 25mg | $336 | In-stock |
| 50mg | $538 | In-stock |
| 100mg | $860 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-U00443 |
| M.Wt: | 338.51 |
| Formula: | C18H30N2O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
SB 258719 is a selective 5-HT7 receptor antagonist with high affinity (pKi=7.5) for the receptor. SB 258719 can be used for the research of cancer and neurological disease[1][2][3]. IC50 & Target: pKi: 7.5(5-HT7)[1][2] In Vitro: SB 258719 (1, 3 and 10 μM; HEK 293 cells) produces a concentration-related rightward-shift of the 5-CT concentration-response curve with no signifcant alteration in the maximal response to 5-CT[1]. In Vivo: SB 258719 (5-20 mg/kg; i.p.) significantly attenuates the 5-CT-induced hypothermia[2].
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