MAK683
CAS No. : 1951408-58-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $143 | In-stock |
| 10mg | $264 | In-stock |
| 25mg | $583 | In-stock |
| 50mg | $869 | In-stock |
| 100mg | $1265 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-103663 |
| M.Wt: | 376.39 |
| Formula: | C20H17FN6O |
| Purity: | >98 % |
| Solubility: | DMSO : 40 mg/mL (ultrasonic) |
MAK683 is an embryonic ectoderm development (EED) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay[1][2]. IC50 & Target: IC50: 59 nM (EED Alphascreen), 89 nM (LC-MS), 26 nM (ELISA)[1] In Vitro: MAK683 has antiproliferative activities in B cell lymphoma cell KARPAS422 after 14 days of treatment with an IC50 of 30 nM[1].
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