Thalidomide-4-O-CH2-COO(t-Bu)
CAS No. : 1950635-36-5
| Size | Price | Stock |
|---|---|---|
| 250mg | $30 | In-stock |
| 1g | $78 | In-stock |
| 5g | $276 | In-stock |
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| Cat. No. : | HY-42771 |
| M.Wt: | 388.37 |
| Formula: | C19H20N2O7 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Thalidomide-4-O-CH2-COO(t-Bu) is t-Bu modified Thalidomide (HY-14658), which is the final step intermediate in the synthesis of Thalidomide-4-OH (HY-123096). Thalidomide-4-O-CH2-COO(t-Bu) acts as a Cereblon ligand to recruit CRBN proteins. The t-Bu protecting group at the end of Thalidomide-4-O-CH2-COO(t-Bu) can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-O-CH2-COO(t-Bu) is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules.
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Inquiry Information- Product Name:
- Thalidomide-4-O-CH2-COO(t-Bu)
- Cat. No.:
- HY-42771
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