Thalidomide-O-amido-C8-NH2 (TFA)


CAS No. : 1950635-16-1

(Synonyms: Cereblon Ligand -Linker Conjugates 2 (TFA); E3 Ligase Ligand-Linker Conjugates 20 (TFA))

1950635-16-1
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Cat. No. : HY-103614
M.Wt: 572.53
Formula: C25H31F3N4O8
Purity: >98 %
Solubility: DMSO : ≥ 131 mg/mL
Introduction of 1950635-16-1 :

Thalidomide-O-amido-C8-NH2 TFA (Cereblon Ligand -Linker Conjugates 2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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