Thalidomide-O-amido-C6-NH2 (TFA)
CAS No. : 1950635-14-9
(Synonyms: Cereblon Ligand-Linker Conjugates 11 (TFA); E3 Ligase Ligand-Linker Conjugates 25 (TFA))
| Size | Price | Stock |
|---|---|---|
| 50mg | $139 | In-stock |
| 100mg | $257 | In-stock |
| 500mg | $1284 | In-stock |
| 1g | $1427 | In-stock |
| 2g | $2853 | In-stock |
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| 10 g | Get quote | |
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| Cat. No. : | HY-112618A |
| M.Wt: | 544.48 |
| Formula: | C23H27F3N4O8 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1]. IC50 & Target: E3 Ligase Ligand-Linker Conjugate[1] In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
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- Thalidomide-O-amido-C6-NH2 (TFA)
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