ARV-771 (Standard)
CAS No. : 1949837-12-0
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| Cat. No. : | HY-100972R |
| M.Wt: | 986.64 |
| Formula: | C49H60ClN9O7S2 |
| Purity: | >98 % |
| Solubility: |
ARV-771 (Standard) is the analytical standard of ARV-771 (HY-100972). This product is intended for research and analytical applications. ARV-771 is a potent BET PROTAC based on E3 ligase von Hippel-Lindau with Kds of 34 nM, 4.7 nM, 8.3 nM, 7.6 nM, 9.6 nM, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively[1].
IC50 & Target:Kd: 4.7 nM (BRD2), 7.6 nM (BRD3), 7.6 nM (BRD4)[1]
IC50: <1 nM (c-MYC protein)[1]
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- ARV-771 (Standard)
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- HY-100972R
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