ATM Inhibitor-10
CAS No. : 1941214-06-7
| Size | Price | Stock |
|---|---|---|
| 1mg | $130 | In-stock |
| 5mg | $325 | In-stock |
| 10mg | $475 | In-stock |
| 25mg | $815 | In-stock |
| 50mg | $1145 | In-stock |
| 100mg | $1536 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-118911 |
| M.Wt: | 434.47 |
| Formula: | C23H23FN6O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO;10 mM in DMSO |
ATM Inhibitor-10 (compound 74), a 3-quinoline carboxamide, is a highly selective and orally active ATM inhibitor (IC50: 0.6 nM). ATM Inhibitor-10 has anti-tumor activity in SW620 xenograft models. ATM Inhibitor-10 is synergistic with Top I inhibitors[1]. IC50 & Target:0.6 nM (ATM), 370 nM (DNAPK), 1.48 μM (mTOR), 0.445 μM (PI3Kα), 12.8 μM (PI3Kβ), 7.1 μM (PI3Kγ)[1]
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