CMPD101 (hydrochloride)


CAS No. : 1941168-71-3

1941168-71-3
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Cat. No. : HY-103045A
M.Wt: 502.92
Formula: C24H22ClF3N6O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1941168-71-3 :

CMPD101 hydrochloride is a novel membrane-permeable, small-molecule inhibitor of both GRK2 and GRK3 with IC50s of 18 nM and 5.4 nM, respectively. CMPD101 hydrochloride also inhibits Rho-associated kinase 2 (ROCK-2) and PKCα (IC50s =1.4 μM and 8.1 μM, respectively)[1].

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