CP-409092
CAS No. : 194098-25-4
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| Cat. No. : | HY-101639 |
| M.Wt: | 297.35 |
| Formula: | C17H19N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 41.67 mg/mL (ultrasonic) |
CP-409092 is a partial agonist of GABAA receptor, with anti-anxiety activity[1]. IC50 & Target: GABAA receptor[1] In Vivo: The pharmacokinetics of CP-409,092 following single intravenous and oral doses of 4 and 15 mg/kg, respectively, are characterized by high clearance of 169+ or -18 mL/min/kg, a volume of distribution of 8.99+ or -1.46 L/kg, and an oral bioavailability of 2.9%+ or -3%. Following oral administration of 100 mg/kg [14C]CP-409,092, the total recovery is 89.1%+ or -3.2% for male rats and 89.3%+ or -0.58% for female rats[1].
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