SRI-31142
CAS No. : 1940118-04-6
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|---|---|---|
| 5mg | $590 | In-stock |
| 10mg | $980 | In-stock |
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| Cat. No. : | HY-117902 |
| M.Wt: | 456.54 |
| Formula: | C29H24N6 |
| Purity: | >98 % |
| Solubility: |
SRI-31142 is a putative, brain-penetrant allosteric inhibitor of the dopamine transporter (DAT). In behavioral studies using intracranial self-stimulation (ICSS), SRI-31142 did not produce the abuse-related effects seen with cocaine and GBR-12935, but instead reduced ICSS responses and dopamine levels in the nucleus accumbens (NAc) at effective doses. SRI-31142 also blocked cocaine-induced increases in ICSS and NAc dopamine[1].
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