Taurolidine
CAS No. : 19388-87-5
| Size | Price | Stock |
|---|---|---|
| 25g | $106 | Get quote |
| 100g | $349 | Get quote |
| 500g | $1221 | Get quote |
| 1 kg | Get quote | |
| 2 kg | Get quote | |
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| Cat. No. : | HY-W011522 |
| M.Wt: | 284.36 |
| Formula: | C7H16N4O4S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 62.5 mg/mL (ultrasonic) |
Taurolidine is a potent antimicrobial and anticancer agent. Taurolidine inhibits cell proliferation. Taurolidine induces apoptosis and autophagy. Taurolidine rescues mice from sepsis-associated lethality[1][2].
In Vitro:Taurolidine (0-500 μM; 24 h) inhibits cell proliferation with IC50s of 150, 55, 23, 119 μM for Saos-2, D17, Hmpos, Cos cells, respectively[1].
Taurolidine (125, 250 µM; 12, 24 h) induces apoptosis[1].
In Vivo:Taurolidine (125 mg/kg; ip; 6 h before CLP or at 6 or 12 h after CLP) improves mouse survival administered at 6 h before CLP and 6 h after cecal ligation and puncture (CLP)[2].
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