Alamifovir
CAS No. : 193681-12-8
(Synonyms: LY582563; MCC-478)
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|---|---|---|
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| Cat. No. : | HY-119691 |
| M.Wt: | 575.42 |
| Formula: | C19H20F6N5O5PS |
| Purity: | >98 % |
| Solubility: | DMSO : 5.75 mg/mL (ultrasonic;warming) |
Alamifovir (LY582563; MCC-478), a purine nucleotide analogue prodrug, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect[1][2]. In Vitro:MCC-478 (0-10 μM) has EC50s of 0.027 μM for wild-type HBV, 2.6 μM for M552I, 3.3 μM for M552V, and 2.0 μM for L528M/M552V[1].
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