SB-216641A
CAS No. : 193611-67-5
(Synonyms: SB-216641 (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 1mg | $70 | In-stock |
| 5mg | $186 | In-stock |
| 10mg | $299 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-103149 |
| M.Wt: | 523.02 |
| Formula: | C28H31ClN4O4 |
| Purity: | >98 % |
| Solubility: | H2O : 26.15 mg/mL (ultrasonic;warming) |
SB-216641A (SB-216641 hydrochloride) is a selective antagonist of 5-HT1B/D receptor. SB-216641A shows high affinity and selectivity for h5-HT1B receptors over h5-HT1D receptors. SB-216641A inhibits the function of SKF-99101H[1][2].
In Vivo:SB-216641A (0.6-20 mg/kg; i.p.; single dose) hinders the SKF-99101H induced hypothermia with dose-dependent manner in guinea pigs[1].
SB-216641A (559 nmol/kg; i.v.; single dose) improves the gastric relaxation observed after injection of 800 nmol/kg Sumatriptan (HY-B0121B) in dogs when combined with 5-HT1B/D receptor antagonist GR-127935[2].
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- HY-103149
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