(Rac)-Lonafarnib


CAS No. : 193275-86-4

(Synonyms: Sch66336 (racemate))

193275-86-4
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Cat. No. : HY-15136B
M.Wt: 638.82
Formula: C27H31Br2ClN4O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 193275-86-4 :

(Rac)-Lonafarnib (Sch66336 racemate) is the racemate of Lonafarnib. Lonafarnib is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras, K-ras and N-ras with IC50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities[1].

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