Capromorelin
CAS No. : 193273-66-4
(Synonyms: CP 424391)
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| Cat. No. : | HY-15242 |
| M.Wt: | 505.61 |
| Formula: | C28H35N5O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Capromorelin (CP 424391) is a pyrazolinone-piperidine dipeptide. Capromorelin is an orally active and potent growth hormone secretagogue (GHS) (hGHS-R1a Ki=7 nM, rat pituicyte EC50=3 nM)[1].
In Vivo:Capromorelin increases plasma GH levels in an anesthesized rat model, with an ED50 value less than 0.05 mg/kg iv[1].
Capromorelin shows enhanced intestinal absorption in rodent models and exhibited superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%, F(dog)=44%][1].
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