L791943
CAS No. : 192767-01-4
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| Cat. No. : | HY-U00254 |
| M.Wt: | 573.38 |
| Formula: | C24H17F10NO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
L791943 is a potent, selective Phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 4.2 nM. IC50 & Target: IC50: 4.2 nM (Phosphodiesterase-4)[1] In Vitro: The extent of metabolism of L791943 is evaluated in vitro in rat hepatocytes and compared to the data obtaine with CDP-840. In our standard incubation conditions, >98% of the parent drug remain in the case of L791943 whereas only 11% of CDP-840 is left intact[2].
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