| Size | Price | Stock |
|---|---|---|
| 1mg | $254 | In-stock |
| 5 mg | Get quote | |
| 10 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-111432 |
| M.Wt: | 455.88 |
| Formula: | C24H20ClF2N3O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
CCG-232601 (compound 8f) is a potent and orally active Rho/MRTF/SRF transcriptional pathway inhibitor. CCG-232601 inhibits the development of Bleomycin-induced dermal fibrosis in mice. CCG-232601 has the potential for the research of antifibrotic for systemic scleroderma[1]. In Vitro: CCG-232601 inhibits SRE.L activity with an IC50 of 0.55 µM[1]. In Vivo: CCG-232601 (50 mg/kg; i.g.; intracutaneous injections of bleomycin; daily for 14 days) inhibits bleomycin-induced skin fibrosis in mice[1].
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