Carboxypeptidase G2 (CPG2) Inhibitor
CAS No. : 192203-60-4
(Synonyms: CPG2 Inhibitor)
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $130 | In-stock |
| 25mg | $230 | In-stock |
| 50mg | $330 | In-stock |
| 100mg | $460 | In-stock |
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| Cat. No. : | HY-70003 |
| M.Wt: | 313.33 |
| Formula: | C13H15NO6S |
| Purity: | >98 % |
| Solubility: | H2O : 1.43 mg/mL (ultrasonic);10 mM in DMSO |
Carboxypeptidase G2 (CPG2) Inhibitor is a novel CPG2 inhibitor with an Ki of 0.3 μM. Carboxypeptidase G2 (CPG2) Inhibitor effectively neutralizes the CPG2 activity in non-tumor sites, allowing for earlier administration of the drug and forming a complementary strategy with antibody clearance strategies. Carboxypeptidase G2 (CPG2) Inhibitor can be used for the study of antibody-directed enzyme prodrug therapy (ADEPT)[1].
In Vitro:Carboxypeptidase G2 (CPG2) Inhibitor (Compound 6d) (0.01-500 μM, 6 d) has no significant cytotoxicity against human colon adenocarcinoma cells LS174T and is suitable for in vivo application[1].
Carboxypeptidase G2 (CPG2) Inhibitor (25-50 μM) exhibits dose-dependent inhibition of the prodrug activation function of CPG2 in LS174T cells[1].
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