Prazosin
CAS No. : 19216-56-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $32 | In-stock |
| 10mg | $50 | In-stock |
| 25mg | $80 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-B0193 |
| M.Wt: | 383.40 |
| Formula: | C19H21N5O4 |
| Purity: | >98 % |
| Solubility: | H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 41.67 mg/mL (ultrasonic;warming;heat to 60°C) |
Prazosin is an α-adrenergic receptor antagonist. Prazosin can reduce inflammation, relieve anxiety, alleviate panic, prevent memory decline, and modulate the pain-relieving effects of opioids. Prazosin can be used in the study of hypertension and Alzheimer’s disease[1][2][3][4].
In Vitro:Prazosin (50 μM, 18 h) can reduce the production of amyloid beta in N2a cells[2].
In Vivo:Prazosin (1 mg/kg, injected into the abdomen once daily, two weeks) can prevent memory deficits in mice by altering the release of inflammatory mediators and astrocytes, alleviating symptoms of Alzheimer's disease[2].
Prazosin (0.1-2 mg/kg, 3-6 mM, administered systemically or locally, in a single dose) can promote fear extinction in mice[3].
Prazosin (0.01-1 mg/kg, subcutaneously, in a single dose) can enhance the analgesic effects of morphine in mice[4].
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