RL648_81


CAS No. : 1919050-87-5

1919050-87-5
Price and Availability of CAS No. : 1919050-87-5
Size Price Stock
5mg $130 In-stock
10mg $220 In-stock
25mg $480 In-stock
50mg $820 In-stock
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Cat. No. : HY-123264
M.Wt: 371.33
Formula: C17H17F4N3O2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 1919050-87-5 :

RL648_81 is a specific KQT-like subfamily 2/3 (KCNQ2/3) activator with an EC50 of 190 nM. RL648_81 robustly shifts the V1/2 of KCNQ2/3 channels towards hyperpolarized potentials.RL648_81 does not shift the V1/2 of either KCNQ4 or KCNQ5.RL648_81 has?the?potential?for?neurologic disorders associated with neuronal hyperexcitability research[1].

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