JAK 3i
CAS No. : 1918238-72-8
Price and Availability of
CAS No. : 1918238-72-8
| Size | Price | Stock |
|---|---|---|
| 1mg | $571 | Get quote |
| 5 mg | Get quote | |
| 10 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-100849 |
| M.Wt: | 354.34 |
| Formula: | C18H15FN4O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Introduction of
1918238-72-8
:
JAK3i is a highly selective JAK3 inhibitor (IC50: 0.43 nM). JAK3i forms a covalent bond with a cysteine in JAK3, but not the closely related kinase domains in JAK1, JAK2, or TYK2. JAK3i abolishes IL-2-driven T-cell proliferation in vivo and has the potential for autoimmune disease research[1].
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