5-HT2 antagonist 1
CAS No. : 191592-09-3
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| Cat. No. : | HY-U00365 |
| M.Wt: | 400.49 |
| Formula: | C22H29FN4O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
5-HT2 antagonist 1 is a potent antagonist of 5-HT2 receptor, with weak α1 adrenoceptor blocking activity. In Vitro: 5-HT2 antagonist 1 shows 45%, 88%, 93% inhibition of 10 μM erotonin-induced contraction at 10 nM, 100 nM, 1000 nM, respectively, in guinea pig mesentcric artery. 5-HT2 antagonist 1 causes 1% and 10% inhibition of 10 μM norepinephrine-induced contraction at 10 and 100 nM, respectively, in guinea pig aorta[1].
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