| Size | Price | Stock |
|---|---|---|
| 100μg | $1200 | Get quote |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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| Cat. No. : | HY-108845 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Tenecteplase (TNK-tPA) is a modified tissue plasminogen activator. Tenecteplase is a recombinant human tissue plasminogen activator (rt-PA) that has been bioengineered to produce mutations in three gene loci. Tenecteplase (TNK-tPA) can be used in the study of acute ischemic stroke[1][2]. In Vitro:Tenecteplase exhibits relatively slight cytotoxicity to neuronal cells compared to its parent compound Alteplase (HY-108865)[3]. In Vivo:Tenecteplase (0.25-2.5 mg/kg, iv, single dose) reduces infarct volume when administered in the first 30 minutes, ameliorates thrombin-induced ischemic thromboembolism in mouse model[3].
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