Solasonine
CAS No. : 19121-58-5
| Size | Price | Stock |
|---|---|---|
| 1mg | $50 | In-stock |
| 5mg | $100 | In-stock |
| 10mg | $160 | In-stock |
| 25mg | $255 | In-stock |
| 50mg | $385 | In-stock |
| 100mg | $575 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-N0070 |
| M.Wt: | 884.06 |
| Formula: | C45H73NO16 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Solasonine is a ferroptosis inducer which can be isolated from Solanum melongena that has anti-infection, anti-cancer, and neurogenesis promoting properties. Solasonine promotes ferroptosis of HCC cells via destruction of the glutathione redox system induced by inhibiting GPX4, and can be used for cancer research[1][2].
In Vitro:Solasonine (2.5-50 ng/mL, 24 h) inhibits cell viability of HepG2 and HepRG in a dose-dependent manner with IC50s of about 15 ng/mL for both HepG2 and HepRG[2].
Solasonine (15 ng/mL, 24 h) significantly increases the proportions of apoptotic HepG2 and HepRG cells from about 4% to more than 20 %[2].
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