Methisazone
CAS No. : 1910-68-5
(Synonyms: Marboran)
| Size | Price | Stock |
|---|---|---|
| 5mg | $65 | In-stock |
| 10mg | $100 | In-stock |
| 25mg | $190 | In-stock |
| 50mg | $300 | In-stock |
| 100mg | $450 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-124564 |
| M.Wt: | 234.28 |
| Formula: | C10H10N4OS |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Methisazone (Marboran) is an antiviral agent that works by inhibiting mRNA and protein synthesis. Methisazone is also a SARS-CoV-2 (COVID-19) inhibitor. Methisazone is mainly used in pox viruses[1]. In Vitro:The EC50 values of methisazone against six vaccinia viruses (Copenhagen, WR, NYC, Elstree, IHD and IHD) in vitro are 3.3, 0.06, 0.3, 0.5, 0.12 and 0.11 μM[3]. In Vivo:Methisazone (10, 30 mg/kg, i.p.; once daily for five days) reduces mortality in female BALB/c mice when started 24-48 hours after VV-IHD virus inoculation and delaies or reduces viral replication in target organs such as liver, spleen, and kidney at a dose of 10 mg/kg[3].
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