BDA-366


CAS No. : 1909226-00-1

1909226-00-1
Price and Availability of CAS No. : 1909226-00-1
Size Price Stock
5mg $130 In-stock
10mg $220 In-stock
25mg $445 In-stock
50mg $600 In-stock
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Cat. No. : HY-101083
M.Wt: 423.50
Formula: C24H29N3O4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1909226-00-1 :

BDA-366 is a potent Bcl2 antagonist (Ki = 3.3 nM), binding Bcl2-BH4 domain with high affinity and selectivity. BDA-366 induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. BDA-366 suppresses growth of lung cancer cells[1].

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