YM928
CAS No. : 190842-36-5
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| Cat. No. : | HY-118814 |
| M.Wt: | 303.77 |
| Formula: | C14H10ClN3OS |
| Purity: | >98 % |
| Solubility: |
YM928 is an orally active and noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist. YM928 inhibits AMPA receptor-mediated toxicity in primary rat hippocampal cultures with an IC50 value of 2 μM. YM928 blocks AMPA-induced intracellular calcium influx with an IC50 value of 3 μM and antagonizes AMPA-induced inward currents with an IC50 value of 1 μM. YM928 is promising for research of neurological disorders[1].
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