Lazertinib
CAS No. : 1903008-80-9
(Synonyms: YH25448; GNS-1480)
| Size | Price | Stock |
|---|---|---|
| 5mg | $121 | In-stock |
| 10mg | $170 | In-stock |
| 25mg | $289 | In-stock |
| 50mg | $420 | In-stock |
| 100mg | $597 | In-stock |
| 500mg | $1380 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-109061 |
| M.Wt: | 554.64 |
| Formula: | C30H34N8O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 3.33 mg/mL (ultrasonic;warming;heat to 60°C) |
Lazertinib (YH25448) is a potent, selective, CNS-penetrant, orally available and irreversible EGFR tyrosine kinase inhibitor, exhibiting high selectivity for activating (EGFRm) and T790M resistance mutations. Lazertinib inhibits phosphorylation of EGFR, AKT and ERK, leading to apoptosis and suppression of tumor growth in mouse H1975-luc brain metastasis xenograft models. Lazertinib can be used in the study of non-small cell lung cancer[1][2]. IC50 & Target:EGFR[1]
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