4-Butylresorcinol
CAS No. : 18979-61-8
(Synonyms: Butylresorcinol)
| Size | Price | Stock |
|---|---|---|
| 1g | $28 | In-stock |
| 5g | $30 | In-stock |
| 10g | $45 | In-stock |
| 25g | $88 | In-stock |
| 100g | $220 | In-stock |
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| Cat. No. : | HY-107369 |
| M.Wt: | 166.22 |
| Formula: | C10H14O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
4-Butylresorcinol is a phenol derivative which can inhibit tyrosinase with IC50 of 11.27 μM. IC50 & Target: IC50: 11.27 μM (4-Butylresorcinol)[1] In Vitro: It shows that 4-Butylresorcinol (4-n-butylresorcinol) significantly inhibits melanin synthesis in a concentration-dependent manner. In addition, it is also found to inhibit the activity of tyrosinase, the rate-limiting melanogenic enzyme. 4-Butylresorcinol does not induce ERK, Akt activation, or MITF degradation, and has no effect on cAMP response element binding protein (CREB) phosphorylation, which stimulates MITF expression. 4-Butylresorcinol strongly reduces tyrosinase activity in a cell-free system. Moreover, 4-Butylresorcinol shows an additive effect in combination with hinokitiol, which reduces MITF expression[2].
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