S1PL-IN-2


CAS No. : 1897406-94-8

1897406-94-8
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Cat. No. : HY-124655
M.Wt: 435.56
Formula: C26H33N3O3
Purity: >98 %
Solubility:
Introduction of 1897406-94-8 :

S1PL-IN-2 (Compound 28) is a potent sphingosine-1-phosphate lyase (S1PL) inhibitor with an IC50 of 120 nM. S1PL-IN-2 shows an IC50 of 230 nM on HEK293 cells. S1PL-IN-2 block the conversion of Vitamin B6 into the active pyridoxal-4-phosphate cofactor required for S1P lyase activity. S1PL-IN-2 can be used for the researches of inflammation and immunology, such as rheumatoid arthritis[1].

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