9-Cyclopentyladenine (monomethanesulfonate)


CAS No. : 189639-09-6

(Synonyms: 9-CP-Ade (mesylate))

189639-09-6
Price and Availability of CAS No. : 189639-09-6
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Cat. No. : HY-116530
M.Wt: 299.35
Formula: C11H17N5O3S
Purity: >98 %
Solubility: DMSO : 41.67 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 189639-09-6 :

9-Cyclopentyladenine monomethylsulfonate (9-CP-Ade mesylate) is a stable non-competitive adenylate cyclase inhibitor with cell permeable properties[1][2]. In Vitro: 9-Cyclopentyladenine monomethanesulfonate (200 μM, 30 min) inhibits the activation of cAMP response element binding protein (CREB) and completely blocks neurogenesis in PC12 cells[1].
9-Cyclopentyladenine monomethanesulfonate (100 μM, 30min) attenuates the effect of relaxin on mechanical activity and prevents relaxin-induced hyperpolarization thereby being involved in the regulation of relaxin on ileal smooth muscle activity in female CD1 Swiss mice[2].
9-Cyclopentyladenine monomethanesulfonate (100 μM, 6 hours) promotes restoration of the keratinocyte permeability barrier by inhibiting the synthesis of cAMP in male hairless mice[3].

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