| Size | Price | Stock |
|---|---|---|
| 5mg | $75 | In-stock |
| 10mg | $128 | In-stock |
| 25mg | $240 | In-stock |
| 50mg | $385 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-N0279 |
| M.Wt: | 270.28 |
| Formula: | C16H14O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Cardamonin can be found from cardamom, and can target various signaling molecules, transcriptional factors, cytokines and enzymes. Cardamonin can inhibit mTOR, NF-κB, Akt, STAT3, Wnt/β-catenin and COX-2. Cardamonin shows anticancer, anti-inflammatory, antimicrobial and antidiabetic activities[1][2].
In Vitro:Cardamonin (5-40 μM, 24 or 48 h) treatment inhibits gastric cancer cell growth[3].
Cardamonin (10-30 μM, 24 or 48 h) treatment can regulate the expression of apoptosis relative protein[3].
Cardamonin (10-30 μM, 24 or 48 h) treatment can inhibit STAT3 phosphorylation[3].
Cardamonin (0-100 μM, 24 h) treatment improves the anti-oxidative capacity in HL-1 cells[4].
In Vivo:Cardamonin (oral gavage; 20, 40 or 80 mg/kg; once) treatments alleviates doxorubicin-induced cardiotoxicity and inhibits apoptosis in doxorubicin-challenged mice[4].
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