Cardamonin


CAS No. : 18956-16-6

(Synonyms: Cardamomin; Alpinetin chalcone)

18956-16-6
Price and Availability of CAS No. : 18956-16-6
Size Price Stock
5mg $75 In-stock
10mg $128 In-stock
25mg $240 In-stock
50mg $385 In-stock
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Cat. No. : HY-N0279
M.Wt: 270.28
Formula: C16H14O4
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 18956-16-6 :

Cardamonin can be found from cardamom, and can target various signaling molecules, transcriptional factors, cytokines and enzymes. Cardamonin can inhibit mTOR, NF-κB, Akt, STAT3, Wnt/β-catenin and COX-2. Cardamonin shows anticancer, anti-inflammatory, antimicrobial and antidiabetic activities[1][2]. In Vitro:Cardamonin (5-40 μM, 24 or 48 h) treatment inhibits gastric cancer cell growth[3].
Cardamonin (10-30 μM, 24 or 48 h) treatment can regulate the expression of apoptosis relative protein[3].
Cardamonin (10-30 μM, 24 or 48 h) treatment can inhibit STAT3 phosphorylation[3].
Cardamonin (0-100 μM, 24 h) treatment improves the anti-oxidative capacity in HL-1 cells[4]. In Vivo:Cardamonin (oral gavage; 20, 40 or 80 mg/kg; once) treatments alleviates doxorubicin-induced cardiotoxicity and inhibits apoptosis in doxorubicin-challenged mice[4].

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