Ceftaroline
CAS No. : 189345-04-8
(Synonyms: T-91825; PPI-0903M)
| Size | Price | Stock |
|---|---|---|
| 1mg | $300 | In-stock |
| 5mg | $750 | In-stock |
| 10 mg | Get quote | |
| 50 mg | Get quote | |
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| Cat. No. : | HY-105049 |
| M.Wt: | 604.70 |
| Formula: | C22H20N8O5S4 |
| Purity: | >98 % |
| Solubility: | DMSO : 85 mg/mL (ultrasonic) |
T-91825 (PPI-0903M), an N-phosphono-type cephalosporin, is the active form of TAK-599. T-91825 is active against both gram-positive and gram-negative bacteria[1][2].
In Vitro: PPI-0903M is very active against S. aureus (MIC50=0.25 μg/mL), including methicillin-resistant (MRSA) strains (MIC50=1 μg/mL)[1].
PPI-0903M is active against hetero-vancomycin-intermediate S. aureus (100 strains), with MIC50s ranging from 0.25 to 4 μg/mL[1].
In Vivo: AK-599 (20 mg/kg; s.c. three times a day for 2 days) decreases the bacterial cell counts in lungs more than 99.9% in a mouse pneumonia model caused by MRSA[2].
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- Ceftaroline
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- HY-105049
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