Mizacorat
CAS No. : 1893415-00-3
(Synonyms: AZD9567)
| Size | Price | Stock |
|---|---|---|
| 1mg | $260 | In-stock |
| 5mg | $650 | In-stock |
| 10mg | $950 | In-stock |
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| Cat. No. : | HY-120012 |
| M.Wt: | 494.53 |
| Formula: | C27H28F2N4O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : < 0.1 mg/mL |
Mizacorat (AZD9567; compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1]. IC50 & Target:IC50: 3.8 nM (Glucocorticoid receptor)[1]. In Vivo:Mizacorat (15 mg/kg/day, Oral gavage daily for 8 days) treatment shows excellent in vivo efficacy in a rat model of joint inflammation[1].
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