CAS No. : 1893-33-0
(Synonyms: Floropipamide (Standard); McN-JR 3345 (Standard); R 3345 (Standard))
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| Cat. No. : | HY-100703R |
| M.Wt: | 375.48 |
| Formula: | C21H30FN3O2 |
| Purity: | >98 % |
| Solubility: |
Pipamperone (Standard) is the analytical standard of Pipamperone (HY-100703). This product is intended for research and analytical applications. Pipamperone (Floropipamide) is a butyrophenone derivative and high-affinity antagonist of 5-HT2A receptor (pKi=8.2) and D4 receptor (pKi=8.0). Pipamperone is also a low-affinity antagonist of D2 receptor (pKi=6.7). Pipamperone affects neurotransmitter functions and exerts antipsychotic activity. Pipamperone is used in the research of mental disorders such as autism-related behavioral disorders and Alzheimer's disease[1][2][3][4]. IC50 & Target:pKi : 8.2 (5-HT2A receptor), 8.0 (D4 receptor), 6.7 (D2 receptor), 7.2 (α1 receptor), 6.9 (5-HT2C receptor), 5.7 (H1 receptor)[1]
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