Chlorasquin
CAS No. : 18921-73-8
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| Cat. No. : | HY-121256 |
| M.Wt: | 458.86 |
| Formula: | C20H19ClN6O5 |
| Purity: | >98 % |
| Solubility: |
Chlorasquin inhibits thymidylate synthetase with an approximate Ki value of 4.9 μM. Chlorasquin is also a folate antagonist, testing the Methotrexate (HY-14519) effect. Chlorasquin binds tighter to dihydrofolate reductase at alkaline pH than does Methotrexate, which is promising for research of antipsoriatic agents[1][2].
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