MNK inhibitor 9


CAS No. : 1889336-59-7

1889336-59-7
Price and Availability of CAS No. : 1889336-59-7
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Cat. No. : HY-124638
M.Wt: 471.56
Formula: C25H29N9O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 1889336-59-7 :

MNK inhibitor 9 is a potent and selective inhibitor of MNK1/2 with IC50 values of 0.003 µM and 0.003 µM for MNK1 and MNK2 respectively. MNK inhibitor 9 has good cell permeability. MNK inhibitor 9 can be used in tumor related research[1]. In Vitro:MNK inhibitor 9 (Compound 9) inhibits the activity of CaMK2D, FLT3, PIM2 and ROCK2 with IC50 values of 0.69 µM, 0.28 µM, 0.73 µM and 0.37 µM, respectively[1].
MNK inhibitor 9 inhibits the proliferation of KMS11-luc human multiple myeloma tumor cell line with an EC50 value of 1.7 µM[1].

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