Antennapedia Peptide
CAS No. : 188842-14-0
(Synonyms: Penetratin peptide)
| Size | Price | Stock |
|---|---|---|
| 1mg | $84 | In-stock |
| 5mg | $210 | In-stock |
| 10mg | $315 | In-stock |
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| Cat. No. : | HY-P0307 |
| M.Wt: | 2246.73 |
| Formula: | C104H168N34O20S |
| Purity: | >98 % |
| Solubility: | H2O |
Antennapedia Peptide (Penetratin peptide) is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides. In Vitro: Antennapedia (Antp)-SMCC-cytochrome c conjugate (5 μg/mL) activates caspase-dependent apoptosis of HeLa cells. The Antp-SMCC-cytochrome c conjugate reduces the clonogenic survival of Hela cells, and inhibits clonogenic survival[1]. ANTP-SmacN7 fusion protein can transduce and accumulate in cells, while SmacN7 alone cannot. ANTP-SmacN7 fusion proteins have a radiation-sensitising effect on EC109 cells. ANTP-SmacN7 combined with radiation does not promote further increases in caspase-3 protein expression, it increases the levels of cleaved caspase-3[2].
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