SC-68448
CAS No. : 188804-07-1
(Synonyms: S 448)
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| Cat. No. : | HY-123864 |
| M.Wt: | 452.29 |
| Formula: | C19H19Cl2N5O4 |
| Purity: | >98 % |
| Solubility: |
SC-68448 (S 448) is a selective αvβ3 antagonist (IC50 = 1 nM). SC-68448 inhibits αvβ3-mediated endothelial cell proliferation. SC-68448 reduces the total level of αvβ6 in NHBE cells. SC-68448 inhibits angiogenesis in a rat corneal neoplasia model. SC-68448 inhibits tumor growth and completely prevents the development of hypercalcemia in a rat Ledich cell tumor model. SC-68448 can be used in research on cardiovascular and cerebrovascular diseases such as hypercalcemia and cancers such as testicular interstitial cell tumors[1][2].
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