Becampanel
CAS No. : 188696-80-2
(Synonyms: AMP 397)
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| Cat. No. : | HY-15073 |
| M.Wt: | 330.19 |
| Formula: | C10H11N4O7P |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Becampanel (AMP397) is the first competitive AMPA antagonist and an antiepileptic agent. In Vitro: Becampanel is negative in a mouse lymphoma tk assay, which includes a 24 h treatment without S9. A weak micronucleus induction in vitro is found at the highest concentrations tested in V79 cells with S9[1]. In Vivo: Becampanel is negative in the following in vivo studies, which includes the maximum tolerated doses of 320 mg/kg in mice and 2000 mg/kg in rats. Becampanel has no genotoxic potential in vivo[1].
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