RdRP-IN-11
CAS No. : 1884574-15-5
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| Cat. No. : | HY-100730 |
| M.Wt: | 492.56 |
| Formula: | C25H20N2O5S2 |
| Purity: | >98 % |
| Solubility: |
RdRP-IN-11 is a non-nucleoside dengue virus RNA-dependent RNA polymerase (RdRp) inhibitor that binds to the palm subdomain of DENV NS5 RdRp, with an IC50 of 23 nM and a Kd of 7 nM. RdRP-IN-11 exhibits antiviral activity against all four dengue serotypes. RdRP-IN-11 can be used for dengue-related research[1].
In Vitro:RdRP-IN-11 (compound 29) exhibits high biochemical potency and binding affinity against DENV-4 NS5 RdRp, with an IC50 of 23 nM and an SPR-Kd of 7 nM[1].
RdRP-IN-11 exhibits antiviral activity against DENV-1, DENV-2, DENV-3, and DENV-4 in A549 cells, with EC50 values of 6.3, 14, 3.8, and 10 μM[1].
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Inquiry Information- Product Name:
- RdRP-IN-11
- Cat. No.:
- HY-100730
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