Foliglurax (dihydrochloride)
CAS No. : 1883329-52-9
(Synonyms: PXT002331 (dihydrochloride))
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| Cat. No. : | HY-108703B |
| M.Wt: | 494.43 |
| Formula: | C23H25Cl2N3O3S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Foliglurax dihydrochloride (PXT002331 dihydrochloride) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 79 nM[1]. Antiparkinsonian effect[1]. In Vitro: Foliglurax, a highly selective and potent mGlu4 receptor PAM with a marked brain-penetrance feature, might revolutionize the field of mGlu4 receptor drug targeting in CNS disorders[2].
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