Foliglurax
CAS No. : 1883329-51-8
(Synonyms: PXT002331)
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| Cat. No. : | HY-108703 |
| M.Wt: | 421.51 |
| Formula: | C23H23N3O3S |
| Purity: | >98 % |
| Solubility: | DMSO : 5.2 mg/mL (ultrasonic;warming) |
Foliglurax (PXT002331) is a highly selective and potent, brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 79 nM[1]. Antiparkinsonian effect[1]. In Vitro: Foliglurax, a highly selective and potent mGlu4 receptor PAM with a marked brain-penetrance feature, might revolutionize the field of mGlu4 receptor drug targeting in CNS disorders[2].
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