3-Hydroxydodecanoic acid


CAS No. : 1883-13-2

1883-13-2
Price and Availability of CAS No. : 1883-13-2
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100mg $106 In-stock
250mg $179 In-stock
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Cat. No. : HY-113107
M.Wt: 216.32
Formula: C12H24O3
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 1883-13-2 :

3-Hydroxydodecanoic acid is a medium-chain fatty acid. 3-Hydroxydodecanoic acid activates GPR84 and promotes IL-12 production. 3-Hydroxydodecanoic acid has anticancer activity against colon cancer, lung cancer, and melanoma[1][2]. In Vitro:3-Hydroxydodecanoic acid (1-100 μM, 1 h) induces lipid peroxidation in rat cerebral cortex, with increasing TBA-RS levels[1].
In Vivo:3-Hydroxydodecanoic acid (i.p., days 6, 9, and 12) shows anti-tumor effect via GPR84 activation and IL-12 production in mice carrying MC38 tumors[2].
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