Palivizumab


CAS No. : 188039-54-5

(Synonyms: MEDI 493)

188039-54-5
Price and Availability of CAS No. : 188039-54-5
Size Price Stock
1mg $280 In-stock
5mg $700 In-stock
10mg $1100 In-stock
25mg $2050 In-stock
50mg $3250 In-stock
100mg $5000 In-stock
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500 mg Get quote
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Cat. No. : HY-P9944
M.Wt: 1000.00
Formula: N/A
Purity: >98 %
Solubility: H2O
Introduction of 188039-54-5 :

Palivizumab (MEDI 493) is a humanized monoclonal antibody against respiratory syncytial virus (RSV). Palivizumab can bind to RSV F protein with a Kd value of 1.4 nM. Palivizumab can prevent respiratory syncytial virus infection in cotton mice[1].
IC50 & Target:RSV-F In Vitro: Palivizumab has RSV neutralizing activity and an EC50 value of 0.95850 nM with IgG1 protein[2].
In Vivo: Palivizumab (0.625-5 mg/kg (i.m.) or 0.312-10 mg/kg (i.v.); single dose) can prevent respiratory syncytial virus infection in cotton mice[1].
Palivizumab (0.05 mg/kg; single dose; intranasally administered)can prevent RSV infection in mice[2].
Palivizumab (15 mg/kg; single dose; s.c.) can inhibit RSV induced airway neurogenic inflammation in rats[3].

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