WKYMVM-NH2
CAS No. : 187986-11-4
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| Cat. No. : | HY-P1121 |
| M.Wt: | 856.11 |
| Formula: | C41H61N9O7S2 |
| Purity: | >98 % |
| Solubility: |
WKYMVM-NH2 is a hexapeptide that activates neutrophils and myeloid cells via the FPRL1 and FPRL2 receptors. It exhibits EC50 values of 2 nM and 80 nM in HL-60-FPRL1 and HL-60-FPRL2 cells, respectively. In HL-60 cells stably expressing FPRL2, WKYMVM-NH₂ induces chemotaxis, with optimal migration observed at concentrations ranging from 10 to 50 nM. It also stimulates superoxide production in neutrophils, with an EC50 of 75 nM. WKYMVM-NH₂ is a useful tool for research in the field of inflammatory diseases[1].
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