Rimeporide


CAS No. : 187870-78-6

(Synonyms: EMD-87580)

187870-78-6
Price and Availability of CAS No. : 187870-78-6
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5mg $130 In-stock
10mg $220 In-stock
25mg $480 In-stock
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Cat. No. : HY-19273
M.Wt: 333.38
Formula: C11H15N3O5S2
Purity: >98 %
Solubility: DMSO : 20 mg/mL (ultrasonic;warming)
Introduction of 187870-78-6 :

Rimeporide (EMD-87580) is a potent and selective inhibitor of the Na+/H+ exchanger (NHE-1). IC50 & Target:NHE1[1] In Vitro: Blocking NHE-1 activity has been shown to decrease intracellular Na+ and Ca2+ overload and pH and Rimeporide (EMD-87580) represents a new therapeutic option for duchenne muscular dystrophy (DMD). Rimeporide (EMD-87580) is expected to act as a muscle-sparing agent and its mode of action means that it is mutation independent[1].

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