PKI-166
CAS No. : 187724-61-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $225 | In-stock |
| 25mg | $400 | In-stock |
| 50mg | $600 | In-stock |
| 100mg | $960 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-117155 |
| M.Wt: | 330.38 |
| Formula: | C20H18N4O |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL |
PKI-166 is a potent, selective and orally bioavailable EGFR tyrosine kinase inhibitor, with an IC50 of 0.7 nM[1].
IC50 & Target: IC50: 0.7 nM (EGFR tyrosine kinase)[1]
In Vitro: Pretreatment with PKI-166 (0-0.5 μM; 1 hour) inhibits EGFR autophosphorylation in human pancreatic cancer cells[1].
PKI-166 (0.03μ M; 6 days) enhanced the cytotoxicity mediated by gemcitabine[1].
In Vivo: PKI-166 (100 mg/kg; p.o.; daily; day 7-day 35 after xenograft) inhibits of pancreatic cancer growth[1].
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- PKI-166
- Cat. No.:
- HY-117155
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